Functional genetic targeting of embryonic kidney.
INTRODUCTION. Tissue development depends on orchestrated signaling and crosstalk between the constituent cell types. This crosstalk is required for the synchronization and balancing of several processes, including regulation of the relative amounts of the distinct components that make up the tissue and, largely in parallel, for the regulation of their spatial organization.
Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention.
This volume details widely used and newer lab protocols for studying hypoxic responses in physiology and diseases. Chapters guide the reader through the application of hypoxic conditions, to the techniques of molecular biology, biochemical, cell biology, genomic,bioinformatic, metabolic, and animal studies.
Biocenter Oulu, Infotech Oulu, Center for Cell Matrix Research, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Aapistie 5A, 90220, Oulu, Finland Zenglai Tan, Jingdong Shan.
Oulu Center for Cell-Matrix Research, and Department of Medical Biochemistry and Molecular Biology, 90014 University of Oulu, Finland. Abstract Formation, maturation, stabilization, and functional efficacy of the neuromuscular junction (NMJ) are orchestrated by transsynaptic and autocrine signals embedded within the synaptic cleft.
Institute of Health Sciences, University of Oulu, Oulu, FinlandDepartment of Medical Biochemistry and Molecular Biology, Oulu Center for Cell-Matrix Research, Biocenter, University of Oulu, Oulu, Finland See all articles by this author.
Background and Aims Early detection of fibrosis is important in identifying individuals at risk for advanced liver disease in non-alcoholic fatty liver disease (NAFLD). We tested whether second-harmonic generation (SHG) and coherent anti-Stokes Raman scattering (CARS) microscopy, detecting fibrillar collagen and fat in a label-free manner, might allow automated and sensitive quantification of.